Original articleER calcium release promotes mitochondrial dysfunction and hepatic cell lipotoxicity in response to palmitate overload
Under a Creative Commons license
open access
Keywords
Metabolic flux analysis
Lipotoxicity
Oxidative stress
ER stress
Fatty liver
Abbreviations
APE
atom percent enrichment
BSA
bovine serum albumin
CAC
citric acid cycle
FFA
free fatty acid
GC–MS
gas chromatography–mass spectrometry
H2DCFDA
2′,7′-dichlorodihydrofluorescein diacetate
MFA
metabolic flux analysis
MUFA
monounsaturated fatty acid
NAFLD
non-alcoholic fatty liver disease
NASH
non-alcoholic steatohepatitis
OA
oleate
PA
palmitate
PI
propidium iodide
ROS
reactive oxygen species
SERCA
sarcoplasmic-endoplasmic reticulum calcium ATPase
SFA
saturated fatty acid
Cited by (0)
Copyright © 2014 The Authors. Published by Elsevier GmbH