Brief communicationGlucose intolerance induced by blockade of central FGF receptors is linked to an acute stress response
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Keywords
Central FGF receptors
FGF receptor inhibitor PD173074
Frequently sampled intravenous glucose tolerance test
Sympathoadrenal response
Minimal model
Glucose metabolism
Abbreviations
AIRg
acute insulin response to glucose
AUC
area under the curve
Ibasal
basal insulin
BIE
basal insulin effect
CNS
central nervous system
DI
disposition index
FGF
fibroblast growth factor
FGFR
fibroblast growth factor receptor
FGF19
Fibroblast growth factor-19
FGFRi
FGFR inhibitor
FSIGT
frequently sampled intravenous glucose tolerance test
GE
glucose effectiveness
GEZI
glucose effectiveness at zero insulin
icv
intracerebroventricular
Kg
glucose disappearance constant
NEFA
non-esterified free fatty acids
SG
glucose effectiveness at basal insulin
SI
insulin sensitivity
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Copyright © 2015 The Authors. Published by Elsevier GmbH