Original ArticleAdipocyte-specific Hypoxia-inducible gene 2 promotes fat deposition and diet-induced insulin resistance☆
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Keywords
Obesity
Adipocyte
Lipid droplet
Lipolysis
Hypoxia-inducible gene 2 (Hig2)
Abbreviations
LD
lipid droplet
Hig2
Hypoxia-inducible gene 2
TG
triglyceride
FFA
free fatty acid
WAT
white adipose tissue
BAT
brown adipose tissue
Ucp1
uncoupling protein 1
HFD
high fat diet
SVF
stromal vascular fraction
SGBS
Simpson-Golabi-Behmel syndrome
eWAT
epididymal white adipose tissue
iWAT
inguinal white adipose tissue
ITT
insulin tolerance test
RER
respiratory exchange ratio
GTT
glucose tolerance test
NEFA
non-esterified fatty acid
Cited by (0)
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This work was supported by the National Institutes of Health Grant: R37-DK030898 to M.P.C.
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Current address: Laboratory for Molecular Medicine, Partners HealthCare, Cambridge, MA, USA.
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Current address: Pfizer, Cambridge, MA, USA.
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Current address: Department of Pathology, Harvard Medical School, Boston, MA, USA.
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Current address: Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
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Current address: Department of Internal Medicine, Touchstone Diabetes Center, The University of Texas Southwestern Medical Center, Dallas, TX, USA.
Copyright © 2016 The Author(s). Published by Elsevier GmbH