Original ArticleMacrophage alternative activation confers protection against lipotoxicity-induced cell death
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Keywords
Obesity
Adipose tissue macrophage
Alternative activation
Lipotoxicity
Meta-inflammation
Abbreviations
M2
alternative activation of macrophage
M1
classic activation of macrophage
WAT
white adipose tissue
ATM
adipose tissue resident macrophage
Ppar
peroxisome proliferator-activated receptor
Stat6
signal transducer and activator of transcription 6
PA
palmitic acid
Nlrp3
NLR family pyrin domain containing 3
BMDM
bone marrow derived macrophage
ILC2
type 2 innate lymphoid cell
SVF
stromal vascular fraction
OCR
oxygen consumption rate
Angptl4
angiopoietin-like 4
Sgms1
sphingomyelin synthase 1
Plin2
perilipin 2
Acadvl
acyl-CoA dehydrogenase, very long chain
Slc25a20
solute carrier family 25 member 20
Mogat1
monoacylglycerol O-acyltransferase 1
Mgl1
macrophage galactose-type lectin-1
Arg1
arginase 1
Bcl2
B-cell lymphoma 2
H2-Eb1
histocompatibility 2, class II antigen E beta
Cited by (0)
- 3
Current address: Institute for Medical Engineering & Science, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
- 4
Current address: l'institut du thorax, INSERM, CNRS, UNIV Nantes & CHU Nantes, Nantes, France.
- 5
Current address: Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 N. Torrey Pines Rd., La Jolla, CA 92037, USA.
© 2017 The Authors. Published by Elsevier GmbH.